Rarerab DSR is a combination medication that contains Rabeprazole (20 mg) and Domperidone (30 mg). It is primarily used to treat conditions related to excessive stomach acid production and digestive motility issues. Here’s a breakdown of each component:

1. Rabeprazole (20 mg):
Class: Proton Pump Inhibitor (PPI).
Mechanism of Action: Rabeprazole works by inhibiting the proton pump in the stomach, reducing the secretion of stomach acid. This helps in managing acid-related conditions like gastroesophageal reflux disease (GERD), peptic ulcers, and acid reflux.
Indications: It is commonly prescribed to reduce stomach acid production, allowing the esophagus and stomach lining to heal from acid-induced damage. It is also used to prevent ulcers caused by NSAIDs (nonsteroidal anti-inflammatory drugs).

2. Domperidone (30 mg):
Class: Prokinetic agent.
Mechanism of Action: Domperidone works by enhancing the movement of the stomach and intestines, facilitating the passage of food through the digestive tract. It also helps prevent nausea and vomiting by blocking dopamine receptors in the gut and brain.
Indications: Domperidone is commonly used to treat symptoms such as nausea, vomiting, bloating, and gastric motility disorders (like delayed gastric emptying).

Combination Uses:
The combination of Rabeprazole and Domperidone is typically used in conditions where acid reflux and poor stomach motility coexist.

This dual action helps in:
Reducing acid reflux and heartburn (thanks to rabeprazole’s acid suppression).
Improving digestion and reducing nausea or bloating (due to domperidone’s prokinetic effect).

Dosage & Administration:
This combination is generally taken before meals, as per the doctor’s recommendation.
The usual dosing frequency is once daily, but it can vary based on the severity of the condition.

Side Effects:
Rabeprazole: Common side effects include headache, diarrhea, abdominal pain, nausea, and dizziness. Long-term use may increase the risk of vitamin B12 deficiency or osteoporosis.
Domperidone: Potential side effects include dry mouth, abdominal cramps, and dizziness. Rarely, domperidone can cause heart-related side effects (such as arrhythmias), especially in high doses or prolonged use.

Precautions:
Rabeprazole: Long-term PPI use may increase the risk of fractures, especially in the elderly, so calcium and vitamin D intake should be monitored.
Domperidone: Should be used with caution in individuals with heart conditions or those taking other medications that affect heart rhythm.

As with any medication, it is important to follow your healthcare provider’s instructions and to inform them of any pre-existing conditions or medications you are currently taking to avoid potential interactions or side effects.